Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410160 | 0.87 | SLC16A3 (0.47) | SLC16A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL19410158 | 0.87 | SLC16A3 (0.47) | SLC16A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL31189237 | 0.87 | SLC16A3 (0.47) | SLC16A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL19410123 | 0.82 | SLC16A3 (0.48) | SLC16A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL19410121 | 0.82 | SLC16A3 (0.48) | SLC16A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL30711155 | 0.82 | SLC16A3 (0.48) | SLC16A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL30711162 | 0.75 | SLC16A3 (0.46) | SLC16A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL19410139 | 0.75 | SLC16A3 (0.46) | SLC16A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL19410138 | 0.75 | SLC16A3 (0.46) | SLC16A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL30711161 | 0.71 | SLC16A3 (0.48) | SLC16A3KDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066445-B2 | Immunomodulators acting as antagonists of PD-1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200172578-A1 | IMMUNOMODULATORS ACTING AS ANTAGONISTS OF PD-1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172578-A1 | IMMUNOMODULATORS ACTING AS ANTAGONISTS OF PD-1 | CD274, PDCD1, PDCD1LG2 | SLC16A3 3333/4885KDM4E 3194/4885ALDH1A1 4359/4885 |
| US-11066445-B2 | Immunomodulators acting as antagonists of PD-1 | CD274, PDCD1, PDCD1LG2 | SLC16A3 3386/4885KDM4E 2895/4885ALDH1A1 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.