Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KYNU | Q16719 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410160 | 1.00 | SLC16A3 (0.47) | SLC16A3ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL19410158 | 1.00 | SLC16A3 (0.47) | SLC16A3ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL19410121 | 0.94 | SLC16A3 (0.48) | SLC16A3ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL19410123 | 0.94 | SLC16A3 (0.48) | SLC16A3ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL30711155 | 0.94 | SLC16A3 (0.48) | SLC16A3ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL22061317 | 0.87 | SLC16A3 (0.44) | SLC16A3ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL19694832 | 0.78 | KYNU (0.56) | ALDH1A1ALOX15KYNUSYKKLK5 | |
| SCHEMBL19694834 | 0.78 | KYNU (0.56) | ALDH1A1ALOX15KYNUSYKKLK5 | |
| SCHEMBL4256075 | 0.78 | KYNU (0.56) | ALDH1A1ALOX15KYNUSYKKLK5 | |
| SCHEMBL25240561 | 0.76 | TACR1 (0.47) | ALDH1A1HTTALOX15SYKCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440097-B1 | MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80/PD-L1 PROTEIN/PROTEIN INTERACTIONS | BRISTOL MYERS SQUIBB CO (US) | 2024-10-23 | — | — | EP | disclosed |