Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060485 | 0.86 | P4HTM (0.50) | MAPK1KDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL69747 | 0.84 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL29508473 | 0.84 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL1018248 | 0.82 | MAPK1 (0.70) | MAPK1KDM4EL3MBTL1ALDH1A1PLA2G1B | |
| SCHEMBL64700 | 0.81 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL423045 | 0.81 | MAPK1 (0.79) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL16185858 | 0.81 | P4HTM (0.46) | MAPK1KDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL22060647 | 0.81 | P4HTM (0.66) | MAPK1KDM4EL3MBTL1ALDH1A1P4HTM | |
| SCHEMBL4295029 | 0.80 | MAPK1 (0.62) | MAPK1KDM4EL3MBTL1ALDH1A1PLA2G1B | |
| SCHEMBL2656944 | 0.80 | CA1 (0.59) | KDM4EL3MBTL1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108538-A1 | RORγ INHIBITOR HAVING SULFONYL STRUCTURE | 正大天晴药业集团股份有限公司 | 2020-06-04 | — | — | WO | disclosed |