SCHEMBL64700

SCHEMBL64700

COC(=O)c1ccc(C(=O)O)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 1.00
KDM4E B2RXH2 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
P4HTM Q9NXG6 17/20 0.66
P4HA1 P13674 1/20 0.66
MIF P14174 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6553707 0.98 MAPK1 (0.96) MAPK1KDM4EL3MBTL1P4HTMP4HA1
SCHEMBL29508473 0.89 MAPK1 (1.00) MAPK1KDM4EL3MBTL1P4HTMP4HA1
SCHEMBL69747 0.89 MAPK1 (1.00) MAPK1KDM4EL3MBTL1P4HTMP4HA1
SCHEMBL14332845 0.86 KDM4E (0.75) MAPK1KDM4EL3MBTL1P4HTMP4HA1
SCHEMBL10284462 0.86 MAPK1 (0.75) MAPK1KDM4EL3MBTL1P4HTMP4HA1
SCHEMBL423045 0.85 MAPK1 (0.79) MAPK1KDM4EL3MBTL1P4HTMP4HA1
SCHEMBL29826109 0.85 MAPK1 (0.79) MAPK1KDM4EL3MBTL1P4HTMP4HA1
SCHEMBL64024 0.85 MAPK1 (0.79) MAPK1KDM4EL3MBTL1P4HTMP4HA1
SCHEMBL5717551 0.84 MAPK1 (0.77) MAPK1KDM4EL3MBTL1P4HTMP4HA1
SCHEMBL378814 0.84 MAPK1 (0.77) MAPK1KDM4EL3MBTL1P4HTMP4HA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 638 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117506232-A Resin tin paste with residual after adhesive welding and preparation method thereof 深圳市鸿慷电子有限公司 2024-02-06 CN claimed
CN-113234013-B Compound for inhibiting collagen synthesis and deposition and application thereof 杭州医学院 2022-05-24 CN claimed
CN-113234013-A Compound for inhibiting collagen synthesis and deposition and application thereof 杭州医学院 2021-08-10 CN claimed
US-6306860-B1 ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS DONG WHA PHARM. INC. CO., LTD. (KR) 2001-10-23 US claimed
CN-1305472-A Novel 2,5-pyridinedicarboxylic acid derivatives DONY WHA PARM IND CO LTD (KR) 2001-07-25 CN claimed
WO-1999058526-A1 NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES DONG WHA PHARM. IND. CO., LTD. (KR) 1999-11-18 WO claimed
US-12590062-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2026-03-31 US disclosed
US-20260078113-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORP (US) 2026-03-19 US disclosed
EP-4694981-A1 HETEROCYCLIC COMPOUNDS AS DUAL INHIBITORS OF PD-L1 AND ADENOSINE RECEPTORS Aurigene Oncology Limited (IN) 2026-02-18 EP disclosed
EP-4688777-A1 NOVEL PD-L1 INHIBITORS Affirma Biotech S. L. (ES) 2026-02-11 EP disclosed
US-20260014174-A1 DUAL INHIBITORS FOR HDAC3 AND HIV-1 PR PURDUE RESEARCH FOUNDATION (US) 2026-01-15 US disclosed
US-12516044-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2026-01-06 US disclosed
EP-3774767-B1 ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF BETH ISRAEL DEACONESS MEDICAL CT INC (US) 2025-10-29 EP disclosed
WO-1996006070-A1 DISUBSTITUTED ARYL AND HETEROARYL IMINES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY ALLERGAN (US) 1996-02-29 WO disclosed
CN-1107144-A Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals HOECHST AG (DE) 1995-08-23 CN disclosed
US-5420145-A Antileukemia Shudo, Koichi (JP) 1995-05-30 US disclosed
US-5364873-A Influencing metabolism of collagen HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-15 US disclosed
EP-0617020-A1 Carboxylic acid derivatives having retinoic acid-like activity Shudo, Koichi, Prof. Dr. (JP) 1994-09-28 EP disclosed
US-5238948-A Influence metabolism of collagen or biosynthesis of C1q HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-24 US disclosed
CN-1060464-A 4-or 5-substituted pyridines-2-carboxylic acid, their preparation method and medicinal HOECHST AG (DE) 1992-04-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014174-A1 DUAL INHIBITORS FOR HDAC3 AND HIV-1 PR HDAC3, HDAC1, HDAC11 MAPK1 769/4885KDM4E 194/4885L3MBTL1 592/4885
US-12590062-B2 PD-1/PD-L1 inhibitors CD274, PDCD1LG2, PDCD1 MAPK1 1183/4885KDM4E 1970/4885L3MBTL1 1047/4885
US-20260078113-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS MSR1, NR3C1, CCR1 MAPK1 3302/4885KDM4E 4270/4885L3MBTL1 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.