Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 13/20 | 0.45 |
| ▸ | TTBK2 | Q6IQ55 | 12/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22061535 | 0.92 | EGFR (0.47) | TTBK1TTBK2EGFRMKNK1AURKA | |
| SCHEMBL22060801 | 0.92 | EGFR (0.47) | TTBK1TTBK2EGFRMKNK1AURKA | |
| Hydrochloric Acid SCHEMBL30662619 | 0.91 | EGFR (0.46) | TTBK1TTBK2EGFRMKNK1AURKA | |
| SCHEMBL22061117 | 0.91 | EGFR (0.46) | TTBK1TTBK2EGFRMKNK1AURKA | |
| Hydrochloric Acid SCHEMBL30662594 | 0.90 | MKNK1 (0.45) | TTBK1TTBK2EGFRMKNK1AURKA | |
| SCHEMBL22061122 | 0.74 | MKNK1 (0.54) | TTBK1TTBK2EGFRMKNK1BRAF | |
| SCHEMBL22061384 | 0.74 | MKNK1 (0.54) | TTBK1TTBK2EGFRMKNK1 | |
| SCHEMBL22061534 | 0.73 | EGFR (0.44) | TTBK1TTBK2EGFRMKNK1BRAF | |
| Hydrochloric Acid SCHEMBL30662605 | 0.73 | MKNK1 (0.53) | TTBK1TTBK2EGFRMKNK1BRAF | |
| Hydrochloric Acid SCHEMBL30662572 | 0.73 | MKNK1 (0.53) | TTBK1TTBK2EGFRMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108619-A1 | MNK INHIBITOR | 上海迪诺医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |