Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22061819 | 1.00 | GRIN1 (0.46) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL30272976 | 0.86 | GRIN1 (0.46) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL21220101 | 0.85 | GRIN1 (0.55) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL25034623 | 0.82 | KMT2A (0.48) | GRIN1GRIN2ASLC6A4OPRK1MEN1 | |
| SCHEMBL22061804 | 0.82 | KMT2A (0.48) | GRIN1GRIN2ASLC6A4OPRK1MEN1 | |
| SCHEMBL30277986 | 0.82 | KMT2A (0.48) | GRIN1GRIN2ASLC6A4OPRK1MEN1 | |
| SCHEMBL30277978 | 0.82 | KMT2A (0.48) | GRIN1GRIN2ASLC6A4OPRK1MEN1 | |
| SCHEMBL21166625 | 0.82 | KMT2A (0.48) | GRIN1GRIN2ASLC6A4OPRK1MEN1 | |
| SCHEMBL4407465 | 0.80 | GRIN1 (0.61) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL22061811 | 0.79 | GRIN1 (0.40) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683262-B2 | Ketamine derivatives and compositions thereof | XW LABORATORIES INC. (KY) | 2020-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683262-B2 | Ketamine derivatives and compositions thereof | OPRK1, KCNK10, KCNK17 | GRIN1 74/4885GRIN2A 54/4885SLC6A4 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.