Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13989319 | 0.85 | GAA (0.73) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL9517500 | 0.84 | ALDH1A1 (0.68) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL1395934 | 0.82 | ALDH1A1 (0.71) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL7363709 | 0.82 | ALDH1A1 (0.66) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL7895751 | 0.81 | ALDH1A1 (0.64) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL2643316 | 0.80 | GAA (0.61) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL1299935 | 0.80 | MAPT (0.61) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL20130642 | 0.79 | MEN1 (0.66) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL29561665 | 0.79 | KMT2A (0.66) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL14465834 | 0.79 | ALDH1A1 (0.62) | ALDH1A1RAB9AHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189056-B1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2020-06-10 | — | — | EP | disclosed |