SCHEMBL7895751

SCHEMBL7895751

CCC(=O)Nc1ccc(C(N)=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
RAB9A P51151 3/20 0.64
HPGD P15428 1/20 0.64
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA9 Q16790 1/20 0.59
SMN1; SMN2 Q16637 4/20 0.58
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
MAPK1 P28482 1/20 0.58
MAPT P10636 2/20 0.58
GAA P10253 2/20 0.58
ATM Q13315 1/20 0.58
HSD17B10 Q99714 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
NPC1 O15118 1/20 0.55
POLB P06746 1/20 0.54
TP53 P04637 1/20 0.52
RECQL P46063 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzamide SCHEMBL27225883 0.87 ALDH1A1 (0.68) ALDH1A1RAB9AHPGDSMN1; SMN2KMT2A
SCHEMBL13989319 0.85 GAA (0.73) ALDH1A1RAB9AHPGDCA12CA1
SCHEMBL21673463 0.85 TP53 (0.68) ALDH1A1RAB9AHPGDCA12CA1
SCHEMBL1189501 0.85 F2 (0.65) ALDH1A1RAB9AHPGDCA12CA1
SCHEMBL9517500 0.84 ALDH1A1 (0.68) ALDH1A1RAB9AHPGDCA12CA1
SCHEMBL2568204 0.83 CA1 (0.60) ALDH1A1RAB9ACA1CA2SMN1; SMN2
SCHEMBL6934236 0.82 CA1 (0.58) ALDH1A1CA1CA2SMN1; SMN2KMT2A
SCHEMBL1395934 0.82 ALDH1A1 (0.71) ALDH1A1RAB9AHPGDCA12CA1
SCHEMBL7363709 0.82 ALDH1A1 (0.66) ALDH1A1RAB9AHPGDSMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL6930363 0.81 CA1 (0.56) ALDH1A1CA1CA2SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3836912-B1 COMBINATIONS OF SUBSTITUTED BENZAMIDES AND 5-ASA AGENTS PHARMACYL AB (SE) 2024-05-01 EP claimed
WO-2023122212-A2 SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS SOUTHERN RESEARCH INSTITUTE (US) 2023-06-29 WO disclosed
WO-2022078524-A2 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-04-21 WO disclosed
EP-2290012-B1 NANOSCALE PIGMENT PARTICLE COMPOSITION AND PROCESS FOR PRODUCING THE SAME XEROX CORP (US) 2017-10-18 EP disclosed
EP-2305759-B1 NONPOLAR LIQUID AND SOLID PHASE CHANGE INK COMPOSITIONS COMPRISING NANOSIZED PARTTICLES OF BENZIMIDAZOLONE PIGMENTS XEROX CORP (US) 2017-09-06 EP disclosed
WO-2010065717-A1 MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2010-06-10 WO disclosed
EP-1889846-A1 Purine derivatives as A2a agonists Novartis AG (CH) 2008-02-20 EP disclosed
WO-2008006563-A1 PURINE DERIVATIVES AS A2A AGONISTS NOVARTIS AG (CH) 2008-01-17 WO disclosed