Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17570950 | 0.84 | RECQL (0.66) | RECQLGAATSHRLMNAALDH1A1 | |
| SCHEMBL22987343 | 0.84 | RECQL (0.66) | RECQLGAATSHRLMNAALDH1A1 | |
| SCHEMBL25908042 | 0.80 | RECQL (0.66) | RECQLGAATSHRLMNAALDH1A1 | |
| SCHEMBL24258940 | 0.79 | RECQL (0.70) | RECQLGAATSHRLMNAALDH1A1 | |
| SCHEMBL23085256 | 0.79 | RECQL (0.83) | RECQLGAATSHRLMNAALDH1A1 | |
| SCHEMBL1203180 | 0.77 | RECQL (0.67) | RECQLGAATSHRLMNAALDH1A1 | |
| SCHEMBL18411703 | 0.77 | RECQL (0.56) | RECQLGAATSHRLMNAALDH1A1 | |
| SCHEMBL22064576 | 0.77 | RECQL (0.56) | RECQLGAATSHRLMNAALDH1A1 | |
| SCHEMBL13376978 | 0.77 | RECQL (0.65) | RECQLGAATSHRLMNAALDH1A1 | |
| SCHEMBL22064133 | 0.76 | RECQL (0.59) | RECQLGAATSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189056-B1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2020-06-10 | — | — | EP | disclosed |