Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17570950 | 1.00 | RECQL (0.66) | RECQLTSHRFAAHGAAMEN1 | |
| SCHEMBL31336136 | 0.87 | RECQL (0.81) | RECQLTSHRFAAHGAAMEN1 | |
| SCHEMBL30838573 | 0.87 | RECQL (0.81) | RECQLTSHRFAAHGAAMEN1 | |
| SCHEMBL30838583 | 0.87 | RECQL (0.81) | RECQLTSHRFAAHGAAMEN1 | |
| SCHEMBL30838584 | 0.87 | RECQL (0.81) | RECQLTSHRFAAHGAAMEN1 | |
| SCHEMBL25908042 | 0.85 | RECQL (0.66) | RECQLTSHRFAAHGAAMEN1 | |
| SCHEMBL13286460 | 0.84 | RECQL (0.57) | RECQLTSHRFAAHGAAMEN1 | |
| SCHEMBL22064151 | 0.84 | RECQL (0.63) | RECQLTSHRFAAHGAAMEN1 | |
| SCHEMBL8466257 | 0.82 | ALDH1A1 (0.58) | RECQLTSHRFAAHGAAMEN1 | |
| SCHEMBL24753945 | 0.82 | PTPN1 (0.52) | RECQLTSHRFAAHGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |