Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18411703 | 1.00 | RECQL (0.56) | RECQLFAAHALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25052996 | 0.85 | FAAH (0.50) | RECQLFAAHALDH1A1SMN1; SMN2SLC6A5 | |
| SCHEMBL25052762 | 0.84 | FAAH (0.64) | RECQLFAAHALDH1A1SMN1; SMN2SLC6A5 | |
| SCHEMBL31164830 | 0.83 | FAAH (0.48) | RECQLFAAHALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20503295 | 0.83 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL2370383 | 0.83 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL9829935 | 0.83 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL2370661 | 0.83 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL9829925 | 0.83 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL27970567 | 0.83 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4163284-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| EP-3313884-B9 | ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | IMMUNOGEN INC (US) | 2021-05-19 | — | — | EP | disclosed |
| EP-3778602-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3189056-B1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2020-06-10 | — | — | EP | disclosed |