SCHEMBL22064348

SCHEMBL22064348

CCc1ccc(COC(=O)c2ccc(Cn3ccnc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 8/20 0.60
TBXAS1 P24557 8/20 0.55
PDE4A P27815 1/20 0.54
PDE4B Q07343 1/20 0.54
PDE4C Q08493 1/20 0.54
PDE4D Q08499 1/20 0.54
CYP11B1 P15538 2/20 0.51
CYP11B2 P19099 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20601870 0.95 CYP19A1 (0.66) CYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL16684296 0.88 TBXAS1 (0.64) CYP19A1TBXAS1PDE4APDE4BPDE4C
SCHEMBL6033876 0.82 CYP19A1 (0.69) CYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL20601853 0.82 CYP19A1 (0.62) CYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL306338 0.82 CYP11B1 (0.73) CYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL10674015 0.82 CYP19A1 (0.59) CYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL20623014 0.81 TBXAS1 (0.62) CYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL6668579 0.78 KMT2A (0.74)
SCHEMBL10674009 0.78 CYP19A1 (0.60) CYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL12639833 0.78 CYP19A1 (0.68) CYP19A1TBXAS1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200181122-A1 Degradable Imidazolium Oligomer and Polymer for Antimicrobial Applications AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181122-A1 Degradable Imidazolium Oligomer and Polymer for Antimicrobial Applications NOD2, CFTR, PUF60 CYP19A1 4646/4885TBXAS1 2982/4885PDE4A 3748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.