Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20709081 | 0.89 | GPR119 (0.38) | GPR119NSD2PDE4BPDE4APDE4C | |
| SCHEMBL30727149 | 0.89 | GPR119 (0.38) | GPR119NSD2PDE4BPDE4APDE4C | |
| SCHEMBL28405729 | 0.89 | GPR119 (0.38) | GPR119NSD2PDE4BPDE4APDE4C | |
| SCHEMBL22064466 | 0.87 | GPR119 (0.37) | GPR119NSD2PDE4BPDE4APDE4C | |
| SCHEMBL5048849 | 0.79 | GPR119 (0.42) | GPR119NSD2PDE4BPDE4APDE4C | |
| SCHEMBL5048852 | 0.79 | GPR119 (0.42) | GPR119NSD2PDE4BPDE4APDE4C | |
| SCHEMBL21473543 | 0.75 | STS (0.37) | GPR119NSD2PDE4BPDE4APDE4C | |
| SCHEMBL21481104 | 0.74 | TBK1 (0.36) | NSD2TBK1EGFR | |
| SCHEMBL30126189 | 0.74 | NSD2 (0.35) | GPR119NSD2PDE4BEHMT2PIK3CD | |
| SCHEMBL30125949 | 0.74 | NSD2 (0.35) | GPR119NSD2PDE4BEHMT2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438107-B1 | SUBSTITUTED QUINAZOLINE COMPOUND HAVING BLOOD-BRAIN BARRIER PENETRATION CAPABILITY | WEISHANG SHANGHAI BIO PHARMACEUTICAL CO LTD (CN) | 2020-06-10 | — | — | EP | disclosed |