Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503295 | 1.00 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL27970567 | 1.00 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL9829925 | 1.00 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL2370383 | 1.00 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL2370661 | 1.00 | FAAH (0.67) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL27970706 | 0.98 | FAAH (0.65) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL2380992 | 0.98 | FAAH (0.65) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL25052762 | 0.98 | FAAH (0.64) | FAAHSMN1; SMN2SLC6A5PSMB5MEN1 | |
| SCHEMBL10605871 | 0.89 | NOD1 (0.68) | FAAHSMN1; SMN2SLC6A5NOD1 | |
| SCHEMBL12350003 | 0.88 | FAAH (0.81) | FAAHSMN1; SMN2SLC6A5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |