SCHEMBL22064602

SCHEMBL22064602

CCCC1=COC(c2ccc(-c3ccc(OCC)c(F)c3F)cc2)CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.32
FPR2 P25090 3/20 0.32
FFAR4 Q5NUL3 1/20 0.31
LTB4R Q15722 1/20 0.30
LTB4R2 Q9NPC1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17068717 0.99 KDM1A (0.32) KDM1AFPR2FFAR4
SCHEMBL17068675 0.93 ESR1 (0.32) KDM1AFPR2
SCHEMBL17068680 0.86 MAPT (0.33) KDM1A
SCHEMBL22064642 0.85 KDM1A (0.34) KDM1AFPR2FFAR4
SCHEMBL17070653 0.85 KDM1A (0.34) KDM1AFPR2FFAR4
SCHEMBL17068713 0.84 FPR2 (0.31) FPR2
SCHEMBL17068678 0.83 KDM1A (0.31) KDM1A
SCHEMBL17068683 0.83 KDM1A (0.31) KDM1A
SCHEMBL17068592 0.82 KDM1A (0.31) KDM1A
SCHEMBL17068715 0.80 FPR2 (0.31) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200183203-A1 REVERSE MODE LIQUID CRYSTAL DEVICE JNC CORPORATION (JP) 2020-06-11 US disclosed