SCHEMBL17070653

SCHEMBL17070653

CCOc1ccc(-c2ccc(C3CCC(C)=CO3)cc2)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.34
FPR2 P25090 6/20 0.33
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
ESR1 P03372 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22064642 0.88 KDM1A (0.34) KDM1AFPR2FGFR1FGFR2ESR1
SCHEMBL22064602 0.85 KDM1A (0.32) KDM1AFPR2FFAR4
SCHEMBL17068717 0.84 KDM1A (0.32) KDM1AFPR2FFAR4
SCHEMBL17070652 0.83 S1PR1 (0.31) KDM1AFPR2FGFR1FGFR2
SCHEMBL17068675 0.83 ESR1 (0.32) KDM1AFPR2ESR1
SCHEMBL17070636 0.81 KDM1A (0.51) KDM1A
SCHEMBL17068715 0.80 FPR2 (0.31) FPR2
SCHEMBL9899628 0.80 KDM1A (0.38) KDM1AFPR2FGFR1FGFR2FFAR4
SCHEMBL17070637 0.80 KDM1A (0.33) KDM1A
SCHEMBL17070645 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523038-B2 Dihydropyran compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-12-20 US disclosed
US-20150252264-A1 DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150252264-A1 DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DRD1, CNKSR1, DRG1 KDM1A 1110/4885FPR2 1315/4885FGFR1 2013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.