SCHEMBL22065077

SCHEMBL22065077

N#Cc1ccnc(-c2ccc(N3c4ccccc4C4(c5ccccc5Oc5ccccc54)c4ccccc43)cc2)c1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 2/20 0.35
GRM5 P41594 10/20 0.34
EGLN1 Q9GZT9 1/20 0.33
TGFBR1 P36897 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
KDM4C Q9H3R0 1/20 0.31
ABCC9 O60706 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22065078 0.90 GRM5 (0.39) USP30GRM5TGFBR1KDM4EALDH1A1
SCHEMBL22064942 0.88 PDK2 (0.37) USP30GRM5EGLN1TGFBR1
SCHEMBL22064943 0.86 EGLN1 (0.36) USP30GRM5EGLN1TGFBR1KDM4E
SCHEMBL22065909 0.85 HCRTR1 (0.32) GRM5KDM4EALDH1A1MAPTTSHR
SCHEMBL22064940 0.83 PGR (0.39) USP30GRM5EGLN1TGFBR1KDM4E
SCHEMBL21928117 0.81 GRM5 (0.38) USP30GRM5KDM4EALDH1A1MAPT
SCHEMBL22065096 0.79 PGR (0.31) KDM4EMAPTTSHR
SCHEMBL21928468 0.79 TGFBR1 (0.38) USP30GRM5TGFBR1KDM4EALDH1A1
SCHEMBL21927309 0.79 GRM5 (0.41) USP30GRM5KDM4EALDH1A1MAPT
SCHEMBL22302366 0.77 MYC (0.40) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200185616-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME LG DISPLAY CO., LTD (KR) 2020-06-11 US disclosed