SCHEMBL22065417

SCHEMBL22065417

N#Cc1ccc(-c2ccc3cc(-c4cc(-c5ccc6ccc7cccnc7c6n5)c5ccccc5c4)ccc3c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 5/20 0.44
CYP11B1 P15538 4/20 0.44
CYP17A1 P05093 2/20 0.44
PIM1 P11309 1/20 0.41
FABP1 P07148 1/20 0.41
SLC40A1 Q9NP59 1/20 0.40
EGLN1 Q9GZT9 1/20 0.37
PDPK1 O15530 1/20 0.37
GLO1 Q04760 1/20 0.37
PARP1 P09874 1/20 0.37
KDM4E B2RXH2 1/20 0.36
GMNN O75496 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
HSP90AA1 P07900 1/20 0.36
MMP2 P08253 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
MMP9 P14780 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22065421 0.97 CYP11B2 (0.41) CYP11B2CYP11B1CYP17A1PIM1FABP1
SCHEMBL22065312 0.96 CYP11B2 (0.41) CYP11B2CYP11B1CYP17A1PIM1FABP1
SCHEMBL22065420 0.92 FABP1 (0.45) CYP11B2CYP11B1CYP17A1PIM1FABP1
SCHEMBL22064703 0.92 CYP11B2 (0.43) CYP11B2CYP11B1CYP17A1PIM1FABP1
SCHEMBL22064725 0.92 FABP1 (0.42) CYP11B2CYP11B1CYP17A1PIM1FABP1
SCHEMBL22065142 0.91 FABP1 (0.44) CYP11B2CYP11B1CYP17A1PIM1FABP1
SCHEMBL22065161 0.90 FABP1 (0.45) CYP11B2CYP11B1CYP17A1PIM1FABP1
SCHEMBL22065163 0.90 CYP11B2 (0.45) CYP11B2CYP11B1CYP17A1PIM1FABP1
SCHEMBL22065461 0.89 FABP1 (0.41) CYP11B2CYP11B1CYP17A1PIM1FABP1
SCHEMBL22064714 0.87 CYP11B2 (0.47) CYP11B2CYP11B1CYP17A1FABP1SLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200181096-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181096-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CYP1A1, AHR CYP11B2 701/4885CYP11B1 483/4885CYP17A1 675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.