SCHEMBL22065482

SCHEMBL22065482

O=C(O)COc1ccc(C(=O)c2cc(C(=O)c3ccc(OCC(=O)O)cc3)cc(C(=O)c3ccc(OCC(=O)O)cc3)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.59
ALDH1A1 P00352 3/20 0.55
PTPN7 P35236 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
FFAR1 O14842 1/20 0.53
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
KMT2A Q03164 1/20 0.51
PTPN12 Q05209 1/20 0.51
GAA P10253 1/20 0.51
PPARA Q07869 1/20 0.51
PPARG P37231 1/20 0.49
PPARD Q03181 1/20 0.49
TSHR P16473 2/20 0.49
SRD5A2 P31213 1/20 0.49
HSD17B10 Q99714 1/20 0.49
NR4A1 P22736 1/20 0.49
APEX1 P27695 1/20 0.49
MCL1 Q07820 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16035699 0.94 ALOX15 (0.65) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1
SCHEMBL38789 0.89 ALOX15 (0.70) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1
SCHEMBL11261731 0.87 ESR1 (0.60) ALOX15ALDH1A1SMN1; SMN2FFAR1MAPT
SCHEMBL17946627 0.85 HPGD (0.58) ALOX15ALDH1A1SMN1; SMN2FFAR1MAPT
SCHEMBL10428800 0.85 LMNA (0.58) ALOX15ALDH1A1SMN1; SMN2MEN1MAPT
SCHEMBL38710 0.85 ALOX15 (0.55) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1
SCHEMBL27686481 0.85 SMN1; SMN2 (0.59) ALOX15ALDH1A1SMN1; SMN2MEN1MAPT
SCHEMBL27707540 0.84 GAA (0.65) ALOX15ALDH1A1PTPN7FFAR1MEN1
SCHEMBL16090174 0.83 ALOX15 (0.49) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1
SCHEMBL339492 0.83 ALOX15 (0.81) ALOX15ALDH1A1PTPN7SMN1; SMN2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030774-B2 Surface-modified inorganic nitride, composition, thermally conductive material, and device with thermally conductive layer FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
US-12030774-B2 Surface-modified inorganic nitride, composition, thermally conductive material, and device with thermally conductive layer FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
US-20200180957-A1 SURFACE-MODIFIED INORGANIC NITRIDE, COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORPORATION (JP) 2020-06-11 US disclosed