SCHEMBL2206586

SCHEMBL2206586

NC(=S)c1ccc(C(N)=S)cc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
MAPT P10636 1/20 0.45
PKM P14618 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PRKCI P41743 1/20 0.43
ASH1L Q9NR48 3/20 0.39
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
LMNA P02545 2/20 0.37
TSHR P16473 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 1/20 0.37
MASP2 O00187 1/20 0.36
PLAU P00749 1/20 0.36
THPO P40225 1/20 0.36
ATM Q13315 1/20 0.36
ATR Q13535 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14018619 0.87 HTT (0.58) HTTSMN1; SMN2MAPTPKMHSD17B10
SCHEMBL469734 0.87 LMNA (0.55) HTTSMN1; SMN2MAPTPKMHSD17B10
SCHEMBL354613 0.85 HTT (0.56) HTTSMN1; SMN2MAPTHSD17B10POLB
SCHEMBL19356884 0.85 HTT (0.50) HTTSMN1; SMN2MAPTPKMHSD17B10
SCHEMBL202776 0.85 SMN1; SMN2 (0.56) HTTSMN1; SMN2LMNA
SCHEMBL999667 0.85 HTT (0.50) HTTSMN1; SMN2PLAU
SCHEMBL10503095 0.85 HTT (0.50) HTTSMN1; SMN2MAPTPKMHSD17B10
SCHEMBL353975 0.85 HTT (0.50) HTTSMN1; SMN2PLAU
SCHEMBL22130014 0.85 HTT (0.50) HTTSMN1; SMN2PLAU
SCHEMBL2304015 0.85 PARP1 (0.55) HTTSMN1; SMN2MAPTHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025081371-A1 HIGH PERFORMANCE FRACTURING FOAM AND RELATED METHODS SAUDI ARABIAN OIL COMPANY (SA) 2025-04-24 WO disclosed
US-8273412-B2 Method for applying corrosion protection layers comprising thioamides to metallic surfaces BASF AKTIENGESELLSCHAFT (DE) 2012-09-25 US disclosed
CN-101111573-B Method for applying corrosion protection layers comprising thioamides to metallic surfaces BASF AG 2012-03-28 CN disclosed
US-7981954-B2 Anti-corrosion coatings containing thioamide groups BASF AKTIENGESELLSCHAFT (DE) 2011-07-19 US disclosed
CN-101685733-A High-temperature thermal fuse device THERM O DISC INC 2010-03-31 CN disclosed
US-20090156736-A1 ANTI-CORROSION COATINGS CONTAINING THIOAMIDE GROUPS BASF AKTIENGESELLSCHAFT (DE) 2009-06-18 US disclosed
US-20080131687-A1 Method For Applying Corrosion Protection Layers Comprising Thioamides To Metallic Surfaces BASF AKTIENGESELLSCHAFT (DE) 2008-06-05 US disclosed
CN-101111573-A Method for applying corrosion protection layers comprising thioamides to metallic surfaces BASF AG (DE) 2008-01-23 CN disclosed
EP-0384144-B1 Pharmaceutical composition for diseases caused by vasoconstriction KOWA CO (JP) 1996-04-03 EP disclosed
EP-0384144-A1 Pharmaceutical composition for diseases caused by vasoconstriction KOWA COMPANY, LTD. (JP) 1990-08-29 EP disclosed
US-4505842-A DOPED POLYOXAZOLES, -THIAZOLES AND -IMIDAZOLES; COATINGS; CASTINGS; WORKABILITY CHEVRON RESEARCH COMPANY (US) 1985-03-19 US disclosed