Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18155125 | 0.92 | ESR1 (0.55) | LMNAHTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL27970358 | 0.88 | MAPK1 (0.56) | LMNAHTTSMN1; SMN2MAPTALOX15 | |
| SCHEMBL2206586 | 0.87 | HTT (0.62) | LMNAHTTSMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL27405389 | 0.82 | NPC1 (0.61) | SMN1; SMN2ALDH1A1CYP3A4HIF1AKDM4E | |
| Hydroquinone SCHEMBL18203134 | 0.81 | CA2 (0.61) | LMNAMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL14018619 | 0.77 | HTT (0.58) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11673671 | 0.75 | MAPT (0.53) | LMNAHTTSMN1; SMN2MAPTHPGD | |
| SCHEMBL10503095 | 0.74 | HTT (0.50) | LMNAHTTSMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL999667 | 0.74 | HTT (0.50) | HTTSMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL22130014 | 0.74 | HTT (0.50) | HTTSMN1; SMN2ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746860-A1 | HYDROGEN SULPHIDE FOR TOPICAL TREATMENT OF NAIL INFECTION | KING'S COLLEGE LONDON (GB) | 2026-05-27 | — | — | EP | claimed |
| CN-122060333-A | High-temperature-resistant silicon rubber and preparation method and application thereof | 东莞宏强新材料有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-119019771-B | Mining high wear-resisting rubber sleeve cable | 天环线缆集团有限公司 | 2025-03-04 | — | — | CN | claimed |
| WO-2025017299-A1 | HYDROGEN SULPHIDE FOR TOPICAL TREATMENT OF NAIL INFECTION | KING'S COLLEGE LONDON (GB) | 2025-01-23 | — | — | WO | claimed |
| CN-119019771-A | Mining high wear-resisting rubber sleeve cable | 天环线缆集团有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-118845638-A | Choline-based melittin composite ionic liquid preparation as well as preparation method and application thereof | 重庆医科大学 | 2024-10-29 | — | — | CN | claimed |
| CN-118685991-A | Antibacterial deodorizing jacket and processing technology thereof | 温州东昊服饰有限公司 | 2024-09-24 | — | — | CN | claimed |
| EP-4414363-A1 | INDOLYLACETIC DERIVATIVES FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Miuli Pharma S.r.l. (IT) | 2024-08-14 | — | — | EP | claimed |
| CN-117924211-A | Preparation method of febuxostat | 哈药集团技术中心 | 2024-04-26 | — | — | CN | claimed |
| CN-110790720-B | Novel preparation method of febuxostat intermediate | 内蒙古京东药业有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-102086169-A | Preparation method of intermediates of Febuxostat | CHONGQING PHARM RES INST CO | 2011-06-08 | — | — | CN | claimed |
| CN-101412699-A | Preparation of 2-(3-carboxaldehyde-4-hydroxy phenyl)-4-methyl-5-thiazole ethyl formate | SHANGHAI INST PHARM INDUSTRY (CN) | 2009-04-22 | — | — | CN | claimed |
| JP-2007500724-A | — | — | 2007-01-18 | — | — | JP | claimed |
| EP-1651624-A2 | PROCESS FOR THE PREPARATION OF SUBSTITUTED THIAZOLES | Abbott Laboratories (US) | 2006-05-03 | — | — | EP | claimed |
| US-20050075323-A1 | Beta3 adrenergic receptor agonists and uses thereof | PFIZER INC | 2005-04-07 | — | — | US | claimed |
| US-20050075503-A1 | Substituted thiazoles | ABBVIE INC. | 2005-04-07 | — | — | US | claimed |
| WO-2005012273-A2 | PROCESS FOR THE PREPARATION OF SUBSTITUTED THIAZOLES | ABBOTT LABORATORIES (US) | 2005-02-10 | — | — | WO | claimed |
| US-20050027128-A1 | Substituted thiazoles | ABBOTT LABORATORIES | 2005-02-03 | — | — | US | claimed |
| US-20030203913-A1 | Beta3 adrenergic receptor agonists and uses thereof | PFIZER INC. | 2003-10-30 | — | — | US | claimed |
| US-20020052392-A1 | Bita3 adrenergic receptor agonists and uses thereof | DAY ROBERT F (US) | 2002-05-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203913-A1 | Beta3 adrenergic receptor agonists and uses thereof | ADRB3, ADRB1, ADRB2 | LMNA 1468/4885HTT 3936/4885SMN1; SMN2 2178/4885 |
| US-20050027128-A1 | Substituted thiazoles | XDH, TH, TPI1 | LMNA 3986/4885HTT 1192/4885SMN1; SMN2 4667/4885 |
| US-20050075323-A1 | Beta3 adrenergic receptor agonists and uses thereof | ADRB3, ADRB1, ADRB2 | LMNA 1332/4885HTT 3679/4885SMN1; SMN2 2100/4885 |
| US-20050075503-A1 | Substituted thiazoles | XDH, TH, TPI1 | LMNA 3986/4885HTT 1192/4885SMN1; SMN2 4667/4885 |
| US-20020052392-A1 | Bita3 adrenergic receptor agonists and uses thereof | ADRB3, ADRA1A, ADRB1 | LMNA 1800/4885HTT 3700/4885SMN1; SMN2 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.