Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.35 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22066001 | 0.90 | MRGPRX4 (0.43) | BTN3A1ALDH1A1HPGDMRGPRX4GPR34 | |
| SCHEMBL18973562 | 0.89 | BTN3A1 (0.46) | BTN3A1MRGPRX4GPR34ELANESMN1; SMN2 | |
| SCHEMBL22065164 | 0.89 | BTN3A1 (0.40) | BTN3A1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL22065159 | 0.88 | BTN3A1 (0.45) | BTN3A1ALDH1A1GPR34CASP1ELANE | |
| SCHEMBL20833694 | 0.87 | BTN3A1 (0.43) | BTN3A1ALDH1A1KMT2AMRGPRX4CASP1 | |
| SCHEMBL22065646 | 0.87 | POLB (0.41) | BTN3A1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL22066006 | 0.86 | BTN3A1 (0.38) | BTN3A1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL20833580 | 0.85 | BTN3A1 (0.41) | BTN3A1ALDH1A1KMT2AMRGPRX4CASP1 | |
| SCHEMBL22066298 | 0.85 | TACR1 (0.42) | BTN3A1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL22065052 | 0.85 | BTN3A1 (0.38) | BTN3A1ALDH1A1KDM4EKMT2ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2022-12-22 | — | — | US | disclosed |
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PPA1, PPIP5K2, TYMP | BTN3A1 4531/4885ALDH1A1 2573/4885KDM4E 2047/4885 |
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PNP, NTPCR, TYMP | BTN3A1 2948/4885ALDH1A1 2781/4885KDM4E 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.