SCHEMBL22067604

SCHEMBL22067604

C=CCOC(=O)c1ccc(NC(=O)c2cccc(C(=O)Nc3ccc(C(=O)OCC=C)cc3)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
RAB9A P51151 5/20 0.56
NPC1 O15118 4/20 0.56
GAA P10253 1/20 0.56
TP53 P04637 2/20 0.53
ALDH1A1 P00352 2/20 0.53
PKM P14618 2/20 0.53
HPGD P15428 1/20 0.53
MAPK1 P28482 1/20 0.53
MAPT P10636 2/20 0.51
POLB P06746 1/20 0.51
SNCA P37840 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
CYP3A4 P08684 1/20 0.47
PPARA Q07869 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5604917 0.90 NPC1 (0.69) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL9576387 0.86 CYP3A4 (0.58) MEN1KMT2AALDH1A1MAPK1SNCA
SCHEMBL157805 0.83 CYP3A4 (0.61) MEN1KMT2ARAB9ANPC1ALDH1A1
SCHEMBL16372021 0.83 CYP3A4 (0.61) MEN1KMT2ARAB9ANPC1ALDH1A1
SCHEMBL31680576 0.82 RAB9A (0.81) MEN1KMT2ASMN1; SMN2RAB9ANPC1
Isophthalic Acid SCHEMBL28712224 0.82 CYP3A4 (0.53) MEN1KMT2ASMN1; SMN2RAB9ANPC1
Benzene SCHEMBL29140663 0.81 CYP3A4 (0.59) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL175786 0.79 SNCA (0.67) MEN1KMT2ATP53ALDH1A1HPGD
SCHEMBL8458134 0.79 CYP26A1 (0.65) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL27479617 0.79 CYP3A4 (0.53) MEN1KMT2ASMN1; SMN2RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200181317-A1 Bisphenol A-Free Crosslinked Polymer Composition WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2020-06-11 US disclosed