Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 9/20 | 0.65 |
| ▸ | RARA | P10276 | 8/20 | 0.65 |
| ▸ | RARB | P10826 | 6/20 | 0.65 |
| ▸ | RARG | P13631 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | BLVRB | P30043 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887936 | 0.90 | CYP26A1 (0.52) | CYP26A1RARARARBRARGCYP3A4 | |
| SCHEMBL8457429 | 0.87 | RARA (0.56) | CYP26A1RARARARBRARGCYP3A4 | |
| SCHEMBL9007231 | 0.87 | RARA (0.69) | CYP26A1RARARARBRARGCYP3A4 | |
| SCHEMBL8839344 | 0.87 | CYP26A1 (0.54) | CYP26A1RARARARBRARGCYP3A4 | |
| SCHEMBL7876774 | 0.87 | CYP26A1 (0.48) | CYP26A1RARARARBRARGCYP3A4 | |
| SCHEMBL7876777 | 0.87 | CYP26A1 (0.48) | CYP26A1RARARARBRARGCYP3A4 | |
| SCHEMBL28527041 | 0.85 | ALDH1A1 (0.66) | CYP26A1RARARARBRARGCYP3A4 | |
| SCHEMBL8102463 | 0.85 | CYP26A1 (0.47) | CYP26A1RARARARBRARGCYP3A4 | |
| SCHEMBL8102461 | 0.85 | CYP26A1 (0.47) | CYP26A1RARARARBRARGCYP3A4 | |
| SCHEMBL8839136 | 0.84 | RARB (0.52) | CYP26A1RARARARBRARGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869067-A | TREATING DERMATOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1999-02-09 | — | — | US | disclosed |
| US-5753239-A | Bi-aromatic compounds and pharmaceutical and cosmetic compositions | CENTRE INTERNATIONAL DE RECHERCHES DEMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1998-05-19 | — | — | US | disclosed |