Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | DRD1 | P21728 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | DRD5 | P21918 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363798 | 0.90 | DRD2 (0.71) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL13320904 | 0.87 | DRD2 (0.56) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL13320909 | 0.81 | DRD2 (0.56) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL8285596 | 0.77 | DRD2 (0.90) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL13320907 | 0.75 | DRD2 (0.41) | DRD2HTR1ADRD1DRD4DRD5 | |
| Ropinirole SCHEMBL35212 | 0.73 | DRD2 (1.00) | DRD2HTR1ADRD1DRD4DRD5 | |
| Ropinirole SCHEMBL29374522 | 0.73 | DRD2 (1.00) | DRD2HTR1ADRD1DRD4DRD5 | |
| Ropinirole SCHEMBL4623647 | 0.72 | APEX1 (1.00) | DRD2HTR1ADRD1DRD4DRD5 | |
| Ropinirole SCHEMBL16044076 | 0.72 | DRD2 (0.97) | DRD2HTR1ADRD1DRD4DRD5 | |
| Ropinirole SCHEMBL40760 | 0.72 | APEX1 (1.00) | DRD2HTR1ADRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3662927-A2 | VACCINE COMPOSITION | NITTO DENKO CORPORATION (JP) | 2020-06-10 | — | — | EP | disclosed |