SCHEMBL22067643

SCHEMBL22067643

Fc1cccc(N(I)I)c1F

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
BCHE P06276 1/20 0.38
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
REV1 Q9UBZ9 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
TAAR1 Q96RJ0 2/20 0.30
PTGES2 Q9H7Z7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22067646 0.79 ACHE (0.38) CES2CES1SLC6A2SLC6A4SLC6A3
SCHEMBL21279351 0.78 CES2 (0.31) CES2CES1
SCHEMBL22067650 0.77 CES2 (0.36) CES2CES1
SCHEMBL2455081 0.77 CES2 (0.39) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL10922037 0.75 CES2 (0.38) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL7690206 0.75 MAPT (0.46) CES2CES1BCHETAAR1
SCHEMBL187614 0.73 CES2 (0.37) CES2CES1BCHE
SCHEMBL9227090 0.73 CES2 (0.37) CES2CES1BCHE
SCHEMBL30076665 0.73 CES2 (0.37) CES2CES1BCHETAAR1
SCHEMBL9287745 0.73 CES2 (0.37) CES2CES1BCHETAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200185610-A1 ORGANIC ELECTRONIC MATERIAL, INK COMPOSITION, AND ORGANIC ELECTRONIC ELEMENT HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-06-11 US disclosed