Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.65 |
| ▸ | CTSK | P43235 | 3/20 | 0.65 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22068619 | 1.00 | CTSS (0.65) | CTSSCTSKPSENENCA2CTSD | |
| SCHEMBL31139352 | 0.96 | CTSS (0.64) | CTSSCTSKPSENENCA2CTSD | |
| SCHEMBL31139338 | 0.96 | CTSS (0.64) | CTSSCTSKPSENENCA2CTSD | |
| SCHEMBL8492297 | 0.94 | CTSS (0.61) | CTSSCTSKPSENENCA2CTSD | |
| SCHEMBL8492292 | 0.94 | CTSS (0.61) | CTSSCTSKPSENENCA2CTSD | |
| SCHEMBL18766187 | 0.94 | CTSS (0.68) | CTSSCTSKPSENENCA2 | |
| SCHEMBL11405307 | 0.94 | CTSS (0.68) | CTSSCTSKPSENENCA2 | |
| SCHEMBL4122350 | 0.90 | CTSS (0.64) | CTSSCTSKPSENENCA2 | |
| SCHEMBL4122354 | 0.90 | CTSS (0.64) | CTSSCTSKPSENENCA2 | |
| SCHEMBL11570829 | 0.89 | CTSS (0.56) | CTSSCTSKPSENENCA2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2820038-B1 | GLP-1 PRODRUGS | NOVO NORDISK AS (DK) | 2020-06-17 | — | — | EP | disclosed |