Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.61 |
| ▸ | CTSK | P43235 | 3/20 | 0.61 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492292 | 1.00 | CTSS (0.61) | CTSSCTSKPSENENALDH1A1CTSD | |
| SCHEMBL31139338 | 0.99 | CTSS (0.64) | CTSSCTSKPSENENALDH1A1CTSD | |
| SCHEMBL31139352 | 0.99 | CTSS (0.64) | CTSSCTSKPSENENALDH1A1CTSD | |
| SCHEMBL11570829 | 0.95 | CTSS (0.56) | CTSSCTSKPSENENALDH1A1CTSD | |
| SCHEMBL11570820 | 0.95 | CTSS (0.56) | CTSSCTSKPSENENALDH1A1CTSD | |
| SCHEMBL22068618 | 0.94 | CTSS (0.65) | CTSSCTSKPSENENCTSDCA2 | |
| SCHEMBL22068619 | 0.94 | CTSS (0.65) | CTSSCTSKPSENENCTSDCA2 | |
| SCHEMBL11405307 | 0.94 | CTSS (0.68) | CTSSCTSKPSENENALDH1A1CA2 | |
| SCHEMBL18766187 | 0.94 | CTSS (0.68) | CTSSCTSKPSENENALDH1A1CA2 | |
| SCHEMBL3205842 | 0.91 | CTSS (0.67) | CTSSCTSKPSENENALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955434-A | N-TERMINAL FMOC-PROTECTED PEPTIDE COMBINATIONS THAT FORM GELS IN WATER | BRIGHAM & WOMEN'S HOSPITAL (US) | 1999-09-21 | — | — | US | disclosed |
| WO-1995021622-A1 | GEL-FORMING POLYPEPTIDE DERIVATIVES | BRIGHAM & WOMEN'S HOSPITAL (US) | 1995-08-17 | — | — | WO | disclosed |