Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22653502 | 0.89 | MAPK8 (0.39) | MAPK8MAPK10THRBLMNAEGLN1 | |
| SCHEMBL22653503 | 0.88 | MAPK8 (0.39) | MAPK8MAPK10THRBLMNAEGLN1 | |
| SCHEMBL18529453 | 0.86 | LIPE (0.44) | MAOBMAOAMAPK10LMNAMEN1 | |
| SCHEMBL22653500 | 0.85 | KDM4E (0.48) | LMNAMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL21678317 | 0.84 | HRH3 (0.38) | LMNAEGLN1HPGDMEN1ALDH1A1 | |
| SCHEMBL22653507 | 0.83 | LMNA (0.37) | MAPK8MAPK10THRBLMNAEGLN1 | |
| SCHEMBL22653505 | 0.83 | LMNA (0.37) | MAPK8MAPK10THRBLMNAEGLN1 | |
| SCHEMBL20031599 | 0.80 | SCN10A (0.42) | LMNA | |
| SCHEMBL21678309 | 0.79 | LIPE (0.34) | LMNAHTTMAPTLIPE | |
| SCHEMBL19994252 | 0.76 | LMNA (0.35) | MAPK8MAPK10LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3738959-A1 | PREPARATION OF 6-PHENOXY-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | Bayer AG (DE) | 2020-11-18 | — | — | EP | disclosed |
| EP-3738959-A1 | PREPARATION OF 6-PHENOXY-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | Bayer AG (DE) | 2020-11-18 | — | — | EP | disclosed |
| WO-2020120284-A1 | PREPARATION OF 6-HALO-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-18 | — | — | WO | disclosed |
| EP-3666759-A1 | PREPARATION OF 6-HALO-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | Bayer Aktiengesellschaft (DE) | 2020-06-17 | — | — | EP | disclosed |