Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ESRRA | P11474 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | PNLIP | P16233 | 10/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | PARG | Q86W56 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069691 | 0.89 | PNLIP (0.60) | MAPTNPSR1PNLIPSTK39 | |
| SCHEMBL22069693 | 0.88 | ESRRA (0.51) | MEN1KMT2AESRRAMAPTNPSR1 | |
| SCHEMBL22069654 | 0.87 | FFAR1 (0.52) | MEN1KMT2AFNTAFNTBPNLIP | |
| SCHEMBL22069709 | 0.87 | PNLIP (0.51) | MEN1KMT2AESRRAMAPTNPSR1 | |
| SCHEMBL11205308 | 0.83 | PNLIP (0.52) | ESRRAMAPTNPSR1PNLIPFFAR1 | |
| SCHEMBL22069659 | 0.81 | P2RX4 (0.54) | MEN1KMT2AESRRAMAPTPNLIP | |
| SCHEMBL11135545 | 0.81 | MEN1 (0.51) | MEN1KMT2AESRRAMAPTNPSR1 | |
| SCHEMBL24629452 | 0.79 | KMT2A (0.67) | MEN1KMT2AMAPTNPSR1POLB | |
| SCHEMBL29769164 | 0.79 | KMT2A (0.67) | MEN1KMT2AMAPTNPSR1POLB | |
| SCHEMBL23685241 | 0.79 | SMN1; SMN2 (0.63) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |