Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 2/20 | 0.51 |
| ▸ | PNLIP | P16233 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | RNF4 | P78317 | 1/20 | 0.50 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22114358 | 0.89 | RNF4 (0.49) | PNLIPFNTAFNTBRNF4PARG | |
| SCHEMBL22069722 | 0.88 | MEN1 (0.51) | ESRRAPNLIPMAPTNPSR1FFAR1 | |
| SCHEMBL22069558 | 0.88 | FFAR1 (0.50) | PNLIPFFAR1FNTAFNTBRNF4 | |
| SCHEMBL22069619 | 0.87 | PNLIP (0.64) | PNLIPMAPTNPSR1MEN1KMT2A | |
| SCHEMBL31536382 | 0.87 | PNLIP (0.64) | PNLIPMAPTNPSR1MEN1KMT2A | |
| SCHEMBL11205308 | 0.85 | PNLIP (0.52) | ESRRAPNLIPMAPTNPSR1FFAR1 | |
| SCHEMBL22069753 | 0.85 | PNLIP (0.54) | ESRRAPNLIPMAPTNPSR1RNF4 | |
| SCHEMBL11135545 | 0.82 | MEN1 (0.51) | ESRRAPNLIPMAPTNPSR1FFAR1 | |
| SCHEMBL5324688 | 0.79 | SMN1; SMN2 (0.65) | MAPTNPSR1RNF4MEN1KMT2A | |
| SCHEMBL22069748 | 0.79 | MITF (0.58) | PNLIPFNTAFNTBRNF4PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |