Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069798 | 0.74 | PIK3CD (0.33) | — | |
| SCHEMBL22069773 | 0.73 | MAPK1 (0.39) | OPRK1OPRM1OPRL1ALDH1A1LMNA | |
| SCHEMBL22069817 | 0.73 | PIK3CD (0.33) | ALDH1A1 | |
| SCHEMBL22069823 | 0.73 | PIK3CD (0.36) | — | |
| SCHEMBL22069769 | 0.72 | PRKCD (0.35) | OPRM1 | |
| SCHEMBL22069793 | 0.72 | FAAH (0.33) | — | |
| SCHEMBL3009112 | 0.68 | CHRM5 (0.61) | OPRK1OPRM1CHRM5ADRA2CACHE | |
| SCHEMBL16102614 | 0.68 | CHRM5 (0.61) | OPRK1OPRM1CHRM5ADRA2CACHE | |
| SCHEMBL6583551 | 0.68 | CHRM5 (0.61) | OPRK1OPRM1CHRM5ADRA2CACHE | |
| SCHEMBL24926382 | 0.68 | HRH3 (0.34) | CHRM5ADRA2CACHENR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666757-A1 | PROCESS FOR PREPARING A PIPERIDIN-4-ONE | Karl-Franzens-Universität Graz (AT) | 2020-06-17 | — | — | EP | claimed |
| EP-3666757-A1 | PROCESS FOR PREPARING A PIPERIDIN-4-ONE | Karl-Franzens-Universität Graz (AT) | 2020-06-17 | — | — | EP | disclosed |