SCHEMBL22071209

SCHEMBL22071209

Cc1ccc(C2(O)c3ccccc3-c3ccc(Br)cc32)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 7/20 0.51
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KIF11 P52732 1/20 0.36
ALDH1A1 P00352 1/20 0.35
MDM2 Q00987 1/20 0.34
TP53 P04637 2/20 0.34
LMNA P02545 1/20 0.34
PTPRC P08575 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12669181 0.92 PDK2 (0.42) PDK2MEN1KMT2AALDH1A1TP53
SCHEMBL824239 0.87 PDK2 (0.57) PDK2OPRM1OPRD1MEN1KMT2A
SCHEMBL7320511 0.85 PDK2 (0.47) PDK2ESR1ESR2OPRM1MEN1
SCHEMBL26547760 0.85 PDK2 (0.55) PDK2OPRM1OPRD1KIF11
SCHEMBL22237663 0.84 PDK2 (0.51) PDK2ESR1ESR2OPRM1OPRD1
SCHEMBL22237605 0.82 PDK2 (0.49) PDK2ESR1ESR2OPRM1OPRD1
SCHEMBL30968867 0.82 PDK2 (0.49) PDK2ESR1ESR2OPRM1OPRD1
SCHEMBL31483494 0.82 PDK2 (0.53) PDK2OPRM1OPRD1MEN1KMT2A
SCHEMBL3038890 0.82 PDK2 (0.53) PDK2OPRM1OPRD1MEN1KMT2A
SCHEMBL26156862 0.82 POLB (0.51) PDK2ESR1ESR2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3663368-A1 METHOD FOR PRODUCING INK COMPOSITON AND ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-06-10 EP disclosed