Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045575 | 0.87 | LMNA (0.62) | LMNAPOLBALDH1A1NLRP3LPAR1 | |
| SCHEMBL25470257 | 0.82 | LPAR1 (0.53) | LPAR1LPAR3 | |
| SCHEMBL873613 | 0.80 | LMNA (0.76) | LMNAPOLBALDH1A1 | |
| SCHEMBL27672921 | 0.78 | LMNA (0.73) | LMNAPOLBALDH1A1 | |
| SCHEMBL78535 | 0.77 | ALDH1A1 (0.52) | LMNAPOLBALDH1A1NLRP3 | |
| SCHEMBL57588 | 0.77 | ALDH1A1 (0.52) | LMNAPOLBALDH1A1NLRP3 | |
| SCHEMBL78536 | 0.77 | ALDH1A1 (0.52) | LMNAPOLBALDH1A1NLRP3 | |
| SCHEMBL17581872 | 0.75 | LMNA (0.46) | LMNAPOLBALDH1A1NLRP3LPAR1 | |
| Methane SCHEMBL6359900 | 0.75 | ALDH1A1 (0.50) | LMNAPOLBALDH1A1NLRP3 | |
| Water SCHEMBL28213494 | 0.75 | ALDH1A1 (0.50) | LMNAPOLBALDH1A1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020118178-A1 | MONOMETHYL FUMARATE-CARRIER CONJUGATES AND METHODS OF THEIR USE | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-06-11 | — | — | WO | disclosed |