Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23871813 | 0.93 | ABCG2 (0.61) | ABCG2KDM4ECYP3A4MAPTTP53 | |
| SCHEMBL23871821 | 0.83 | ADORA3 (0.57) | ABCG2KDM4ECYP3A4MAPTTP53 | |
| SCHEMBL23871902 | 0.77 | KDM4E (0.53) | ABCG2KDM4ECYP3A4MAPTTP53 | |
| SCHEMBL22033960 | 0.74 | ADORA3 (0.50) | ABCG2KDM4ECYP3A4MAPTTP53 | |
| SCHEMBL15456981 | 0.73 | KDM4E (0.57) | ABCG2KDM4ECYP3A4MAPTTP53 | |
| SCHEMBL2629300 | 0.73 | ABCG2 (1.00) | ABCG2KDM4ECYP3A4MAPTTP53 | |
| SCHEMBL22072726 | 0.72 | ADORA3 (0.48) | ABCG2KDM4ECYP3A4MAPTTP53 | |
| SCHEMBL26145327 | 0.72 | KDM4E (0.74) | KDM4ECYP3A4MAPTTP53LMNA | |
| SCHEMBL15266926 | 0.71 | ADORA3 (0.79) | ABCG2KDM4ECYP3A4MAPTTP53 | |
| SCHEMBL15965556 | 0.70 | KDM4E (0.66) | ABCG2KDM4ECYP3A4MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020118178-A1 | MONOMETHYL FUMARATE-CARRIER CONJUGATES AND METHODS OF THEIR USE | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-06-11 | — | — | WO | disclosed |