Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22072726 | 0.94 | ADORA3 (0.48) | KDM4ECYP3A4ABCG2MEN1MAPK1 | |
| SCHEMBL23871821 | 0.92 | ADORA3 (0.57) | KDM4ECYP3A4ABCG2MEN1MAPK1 | |
| SCHEMBL22033960 | 0.91 | ADORA3 (0.50) | KDM4ECYP3A4ABCG2MEN1MAPK1 | |
| Pentaacetylquercetin SCHEMBL4064499 | 0.81 | ADORA3 (0.77) | KDM4ECYP3A4ABCG2MEN1MAPK1 | |
| SCHEMBL23871813 | 0.81 | ABCG2 (0.61) | KDM4ECYP3A4ABCG2MEN1KMT2A | |
| SCHEMBL24344965 | 0.79 | KDM4E (0.50) | KDM4ECYP3A4ABCG2MEN1MAPK1 | |
| SCHEMBL23278846 | 0.79 | ADORA3 (0.72) | KDM4ECYP3A4ABCG2MEN1MAPK1 | |
| SCHEMBL23483932 | 0.79 | ADORA3 (0.69) | KDM4ECYP3A4ABCG2MEN1MAPK1 | |
| SCHEMBL20581904 | 0.79 | ADORA3 (0.54) | KDM4ECYP3A4ABCG2MEN1MAPK1 | |
| SCHEMBL20581913 | 0.77 | ADORA3 (0.53) | KDM4ECYP3A4ABCG2MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490489-A | Monomethyl fumarate-carrier conjugates and methods of use thereof | 旗舰创业创新五公司 | 2021-10-08 | — | — | CN | disclosed |
| US-20210299079-A1 | MONOMETHYL FUMARATE-CARRIER CONJUGATES AND METHODS OF THEIR USE | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299079-A1 | MONOMETHYL FUMARATE-CARRIER CONJUGATES AND METHODS OF THEIR USE | SLC16A1, SLC16A3, SLC16A8 | KDM4E 343/4885CYP3A4 504/4885ABCG2 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.