SCHEMBL22072070

SCHEMBL22072070

CC1CC2CC(C)C(Nc3ccc(Br)cc3)C(C1)C2

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL737152 0.80 ALDH1A1 (0.44) KDM4EEPHX2
SCHEMBL23655801 0.68 EPHX2 (0.38) EPHX2
SCHEMBL11150138 0.67 EPHX2 (0.39) EPHX2
Hydrochloric Acid SCHEMBL11155742 0.66 EPHX2 (0.38) EPHX2
SCHEMBL22725874 0.65
SCHEMBL18602790 0.65 EPHX2 (0.35) EPHX2
SCHEMBL23057471 0.63 KDM1A (0.41)
SCHEMBL23594273 0.62 KDM1A (0.33)
SCHEMBL5672302 0.62 EPHX2 (0.56) KDM4EEPHX2
SCHEMBL4101119 0.61 EPHX2 (0.68) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020118096-A1 ANTI-CANCER ACTIVITY OF ADAMANTANE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-06-11 WO disclosed