SCHEMBL737152

SCHEMBL737152

Brc1ccc(NC2C3CC4CC(C3)CC2C4)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
EPHX2 P34913 7/20 0.38
P2RX7 Q99572 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
HSP90AA1 P07900 1/20 0.35
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 1/20 0.33
FKBP1A P62942 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11150138 0.81 EPHX2 (0.39) ALDH1A1HTTHSD17B10MEN1KMT2A
SCHEMBL22072070 0.80 KDM4E (0.35) EPHX2KDM4E
Hydrochloric Acid SCHEMBL11155742 0.79 EPHX2 (0.38) ALDH1A1HTTHSD17B10MEN1KMT2A
SCHEMBL5672302 0.79 EPHX2 (0.56) ALDH1A1HTTHSD17B10KMT2AEPHX2
SCHEMBL2390346 0.74 HSD11B1 (0.48) KMT2AEPHX2
SCHEMBL4101119 0.74 EPHX2 (0.68) MEN1KMT2AEPHX2
SCHEMBL11465705 0.73 CYP3A4 (0.57) ALDH1A1HTTHSD17B10MEN1KMT2A
SCHEMBL3363980 0.72 SMN1; SMN2 (0.63) ALDH1A1MEN1KMT2AEPHX2SMN1; SMN2
SCHEMBL11214247 0.70 MAPT (0.42) ALDH1A1HTTMEN1KMT2ASMN1; SMN2
SCHEMBL11449079 0.69 CXCR3 (0.40) MEN1KMT2AP2RX7SMN1; SMN2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734971-A2 DRUG TO TREAT STIMULANT ADDICTION Single Dose Therapeutics, Inc. (US) 2026-05-06 EP claimed
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
WO-2025040956-A2 DRUG TO TREAT STIMULANT ADDICTION RAUTIOLA DAVIN (US) 2025-02-27 WO claimed
US-11576866-B2 Gastric residence systems for sustained delivery of adamantane-class drugs LYNDRA THERAPEUTICS, INC. (US) 2023-02-14 US claimed
WO-2022255867-A1 PROTEIN BIOMARKERS FOR NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2022-12-08 WO claimed
WO-2020191503-A1 METHODS AND USES OF BROMANTANE AND DERIVATIVES THEREOF FOR TREATING LUNG DISEASE, FATTY LIVER DISEASE, AND KIDNEY DISORDERS ALGERNON PHARMACEUTICALS INC. (CA) 2020-10-01 WO claimed
WO-2026107393-A2 AAV CAPSID MODIFICATIONS THAT REDUCE IMMUNOGENICITY THE BROAD INSTITUTE, INC. (US) 2026-05-21 WO disclosed
US-20260130877-A1 TREATMENT OF NEURODEVELOPMENTAL DISORDERS THE REGENTS OF THE UNIV OF CALIFORNIA (US) 2026-05-14 US disclosed
EP-4734971-A2 DRUG TO TREAT STIMULANT ADDICTION Single Dose Therapeutics, Inc. (US) 2026-05-06 EP disclosed
EP-4734971-A2 DRUG TO TREAT STIMULANT ADDICTION Single Dose Therapeutics, Inc. (US) 2026-05-06 EP disclosed
US-12618082-B2 Engineered muscle targeting compositions THE BROAD INSTITUTE, INC. (US) 2026-05-05 US disclosed
US-12605470-B2 Nanodroplet with layer-by-layer assembly ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-04-21 US disclosed
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP disclosed
US-20110028510-A1 Compositions, Methods, and Kits for Treating Influenza Viral Infections COMBINATORX (SINGAPORE) PTE. LTD. (SG) 2011-02-03 US disclosed
WO-2011001258-A1 COMPOSITIONS, METHODS, AND KITS FOR TREATING VIRAL AND BACTERIAL INFECTIONS BY TOCOTRIENOLS, TOCOMONOENOLS, TOCODIENOLS, TOCOPHEROLS, AND THEIR DERIVATES EVITA LIFE SCIENCE PTE. LTD (SG) 2011-01-06 WO disclosed
WO-2010095041-A2 COMPOSITIONS, METHODS, AND KITS FOR TREATING INFLUENZA VIRAL INFECTIONS EXCRX (SINGAPORE) PTE.LTD. (SG) 2010-08-26 WO disclosed
US-20070233401-A1 Spectral measurement with assisted data analysis THERMO ELECTRON SCIENTIFIC INSTRUMENTS LLC 2007-10-04 US disclosed
WO-2007109188-A2 SPECTRAL MEASUREMENT WITH ASSISTED DATA ANALYSIS THERMO ELECTRON SCIENTIFIC INSTRUMENTS LLC (US) 2007-09-27 WO disclosed
US-20060270742-A1 Compositions and methods for the treatment of neurodegenerative diseases COMBINATORX, INC. 2006-11-30 US disclosed
WO-2006119295-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES COMBINATORX, INCORPORATED (US) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618082-B2 Engineered muscle targeting compositions MUSK, MYO3B, MYOF ALDH1A1 4196/4885HTT 3774/4885HSD17B10 3487/4885
US-20060270742-A1 Compositions and methods for the treatment of neurodegenerative diseases PSEN2, PSEN1, HTT ALDH1A1 3571/4885HTT 3/4885HSD17B10 1538/4885
US-20260130877-A1 TREATMENT OF NEURODEVELOPMENTAL DISORDERS EED, ICOS, FABP7 ALDH1A1 756/4885HTT 622/4885HSD17B10 804/4885
US-20110028510-A1 Compositions, Methods, and Kits for Treating Influenza Viral Infections IL5, CCL5, CCL11 ALDH1A1 1992/4885HTT 2121/4885HSD17B10 3762/4885
US-12605470-B2 Nanodroplet with layer-by-layer assembly FLNB, FLNA, DAGLB ALDH1A1 3021/4885HTT 4053/4885HSD17B10 1745/4885
US-11576866-B2 Gastric residence systems for sustained delivery of adamantane-class drugs SLC6A2, SLC10A2, SLC18A2 ALDH1A1 242/4885HTT 1552/4885HSD17B10 1335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.