Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22072182 | 0.80 | SMN1; SMN2 (0.39) | HPGDKDM4EALDH1A1GLASMN1; SMN2 | |
| SCHEMBL22072146 | 0.78 | ALDH1A1 (0.46) | HPGDKDM4EALDH1A1GLASMN1; SMN2 | |
| SCHEMBL22072095 | 0.78 | POLB (0.40) | HPGDKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9704918 | 0.75 | MAPK1 (0.50) | HPGDKDM4EALDH1A1GLASMN1; SMN2 | |
| SCHEMBL22072305 | 0.72 | BRD4 (0.36) | KDM4EMAPTMEN1KMT2AUSP2 | |
| SCHEMBL22071690 | 0.70 | ESR1 (0.46) | HPGDKDM4EALDH1A1GLASMN1; SMN2 | |
| SCHEMBL22071675 | 0.68 | MEN1 (0.47) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL22071668 | 0.68 | MEN1 (0.47) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL22071736 | 0.66 | KMT2A (0.41) | HPGDKDM4EALDH1A1GLASMN1; SMN2 | |
| SCHEMBL22071679 | 0.66 | MEN1 (0.59) | HPGDKDM4EALDH1A1GLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117974-A1 | COMPOUNDS AND COMPOSITIONS FOR EYE TREATMENTS | AVEDRO, INC. (US) | 2020-06-11 | — | — | WO | disclosed |