Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GJB2 | P29033 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21300587 | 0.83 | LMNA (0.42) | LMNADRD1HRH4HRH3PDE4D | |
| SCHEMBL18666894 | 0.80 | HRH4 (0.51) | LMNADRD1HRH4HRH3PTPN1 | |
| SCHEMBL24679813 | 0.80 | HRH4 (0.51) | LMNADRD1HRH4HRH3PTPN1 | |
| SCHEMBL9843718 | 0.80 | PDE4D (0.48) | LMNADRD1PDE4DGJB2TAAR1 | |
| SCHEMBL22992300 | 0.80 | PDE4D (0.48) | LMNADRD1PDE4DGJB2TAAR1 | |
| SCHEMBL24681155 | 0.80 | LMNA (0.44) | LMNADRD1HRH4HRH3PDE4D | |
| SCHEMBL7925903 | 0.80 | LMNA (0.44) | LMNADRD1HRH4HRH3PDE4D | |
| SCHEMBL9844144 | 0.80 | PDE4D (0.48) | LMNADRD1PDE4DGJB2TAAR1 | |
| SCHEMBL10779215 | 0.77 | TYMP (0.37) | — | |
| SCHEMBL9646481 | 0.77 | TYMP (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114418-A1 | ANTICOAGULANT PENTASACCHARIDE COMPOUND, COMPOSITION, AND PREPARATION METHOD AND MEDICAL USE THEREOF | 南京正大天晴制药有限公司 | 2020-06-11 | — | — | WO | disclosed |