SCHEMBL7925903

SCHEMBL7925903

CO[C@H]1O[C@H](COCc2ccccc2)C[C@H]1O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
PDE4D Q08499 1/20 0.43
DRD1 P21728 1/20 0.41
HRH4 Q9H3N8 4/20 0.40
HRH3 Q9Y5N1 4/20 0.40
SLC6A2 P23975 1/20 0.40
GJB2 P29033 1/20 0.39
PTPN1 P18031 2/20 0.39
CDC25B P30305 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
TSHR P16473 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SSTR1 P30872 1/20 0.37
SSTR2 P30874 1/20 0.37
SSTR4 P31391 1/20 0.37
SSTR3 P32745 1/20 0.37
SSTR5 P35346 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24681155 1.00 LMNA (0.44) LMNAPDE4DDRD1HRH4HRH3
SCHEMBL7919303 0.85 LMNA (0.41) LMNAPDE4DDRD1HRH4HRH3
SCHEMBL18699941 0.84 LMNA (0.45) LMNADRD1HRH4HRH3GJB2
SCHEMBL14107745 0.84 LMNA (0.45) LMNADRD1HRH4HRH3GJB2
SCHEMBL19650284 0.84 LMNA (0.45) LMNADRD1HRH4HRH3GJB2
SCHEMBL20762628 0.84 LMNA (0.47) LMNAPDE4DDRD1HRH4HRH3
SCHEMBL459736 0.82 LMNA (0.48) LMNAPDE4DDRD1HRH4HRH3
SCHEMBL16440849 0.82 LMNA (0.43) LMNADRD1HRH4HRH3GJB2
SCHEMBL22073091 0.80 LMNA (0.43) LMNAPDE4DDRD1HRH4HRH3
SCHEMBL14428916 0.78 PDE4D (0.52) PDE4DSLC6A2GJB2PTPN1CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6229008-B1 CHEMICAL INTERMEDIATES FOR VIRICIDES AND ANTICARCINOGENIC AGENTS SAISCHEK JOERN (AT) 2001-05-08 US disclosed
EP-0777673-A2 ALPHA-D-PENTOFURANOSIDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND THEIR USE Saischek, Jörn (AT) 1997-06-11 EP disclosed
WO-1996006103-A2 α-D-PENTOFURANOSIDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND THEIR USE SAISCHEK JOERN (AT) 1996-02-29 WO disclosed