Intermedine

Intermedine

SCHEMBL22076809

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 3/20 0.82
▸ MC5R P33032 2/20 0.82
▸ MC3R P41968 2/20 0.82
▸ MC1R Q01726 2/20 0.82
▸ C5AR1 P21730 2/20 0.70
▸ CTSL P07711 3/20 0.69
▸ CTSS P25774 3/20 0.69
▸ CTSK P43235 3/20 0.69
▸ CTSH P09668 1/20 0.69
▸ IL23R Q5VWK5 1/20 0.64
▸ CXCL8 P10145 5/20 0.63
▸ GLP1R P43220 4/20 0.63
▸ GCGR P47871 3/20 0.60
▸ NMBR P28336 1/20 0.60
▸ GRPR P30550 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Intermedine SCHEMBL20548027 1.00 MC4R (0.82) MC4RMC5RMC3RMC1RC5AR1
SCHEMBL29358645 1.00 MC4R (0.82) MC4RMC5RMC3RMC1RC5AR1
SCHEMBL29534172 0.98 MC4R (0.78) MC4RMC5RMC3RMC1RC5AR1
SCHEMBL29430238 0.96 MC4R (0.78) MC4RMC5RMC3RMC1RC5AR1
SCHEMBL29533733 0.96 MC4R (0.78) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL29419548 0.96 MC4R (0.81) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL22463810 0.96 MC4R (0.81) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL29352792 0.96 MC4R (0.81) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL22463811 0.96 MC4R (0.81) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL29533175 0.95 MC4R (0.80) MC4RMC5RMC3RMC1RC5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 674 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099249-A1 MODIFIED AND UNMODIFIED PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE (PAM) FOR USE IN SUBJECTS HAVING INCREASED AMYLOID-BETA AND/OR PHOSPHO-TAU-PROTEIN LOAD AND/OR NEUROINFLAMMATION PAM THERAGNOSTICS GMBH (DE) 2026-05-15 — — WO claimed
US-20260133154-A1 ELECTROCHEMICAL SHOTGUN TAGGING ASSAY WITH CATALYTIC AMPLIFICATION OXFORD UNIV INNOVATION LIMITED (GB) 2026-05-14 — — US claimed
EP-3532092-B1 IMMUNOGLOBULINS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2026-04-29 — — EP claimed
US-12350488-B2 System and method for intermittent electrical modulation ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) 2025-07-08 — — US claimed
US-12352746-B2 Peptide-comprising electrode OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-07-08 — — US claimed
WO-2025133225-A1 PHARMACEUTICAL COMBINATION OF PEPTIDE-GLY AND PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE (PAM) PAM THERAGNOSTICS GMBH (DE) 2025-06-26 — — WO claimed
US-20250059505-A1 IMPROVED METHODS FOR INDUCING THE MATURATION OF MAMMALIAN CELLS REVERSE BIOENGINEERING INC (US) 2025-02-20 — — US claimed
US-20250026803-A1 IMMUNOGLOBULINS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2025-01-23 — — US claimed
CN-118304263-B Synergistic mild photo-thermal Wen Minzhi plastid guided by photo-acoustic imaging and application 山东大学 2024-11-19 — — CN claimed
US-20240369548-A1 ELECTROCHEMICAL SHOTGUN TAGGING ASSAY OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2024-11-07 — — US claimed
WO-2023283386-A2 SAFER PSYCHOACTIVE COMPOSITIONS ARCADIA MEDICINE, INC. (US) 2023-01-12 — — WO claimed
EP-4110372-A1 USE OF PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE (PAM) FOR THERAPEUTIC PURPOSE PAM Theragnostics GmbH (DE) 2023-01-04 — — EP claimed
EP-4111201-A1 METHODS FOR DETERMINING PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE (PAM) AND ITS USE FOR DIAGNOSTIC PURPOSE PAM Theragnostics GmbH (DE) 2023-01-04 — — EP claimed
WO-2022256720-A2 ENANTIOMERIC ENTACTOGEN COMPOSITIONS AND METHODS OF THEIR USE ARCADIA MEDICINE, INC. (US) 2022-12-08 — — WO claimed
EP-4097458-A1 ANALYTE DETECTION WITH REDOX ACTIVE POLYMER-COATED ELECTRODE Oxford University Innovation Limited (GB) 2022-12-07 — — EP claimed
CN-115227876-A Preparation method of tissue engineering epidermis 福建省海西细胞生物工程有限公司 2022-10-25 — — CN claimed
CN-115181719-A Serum-free medium for culturing tissue engineering epidermis 福建省海西细胞生物工程有限公司 2022-10-14 — — CN claimed
CN-115066254-A Human anti-inflammatory peptides for inhalation treatment of inflammatory lung diseases 阿德维塔生命科学有限责任公司 2022-09-16 — — CN claimed
US-11401315-B2 Immunoglobulins and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2022-08-02 — — US claimed
CN-114317612-A RNA preparations comprising purified modified RNA for reprogramming cells 宾夕法尼亚州大学信托人 2022-04-12 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260133154-A1 ELECTROCHEMICAL SHOTGUN TAGGING ASSAY WITH CATALYTIC AMPLIFICATION BTD, APEX1, ACP1 MC4R 2441/4885MC5R 1670/4885MC3R 1920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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