SCHEMBL29358645

SCHEMBL29358645

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C

nearest known ligand 0.82

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 3/20 0.82
▸ MC5R P33032 2/20 0.82
▸ MC3R P41968 2/20 0.82
▸ MC1R Q01726 2/20 0.82
▸ C5AR1 P21730 2/20 0.70
▸ CTSL P07711 3/20 0.69
▸ CTSS P25774 3/20 0.69
▸ CTSK P43235 3/20 0.69
▸ CTSH P09668 1/20 0.69
▸ IL23R Q5VWK5 1/20 0.64
▸ CXCL8 P10145 5/20 0.63
▸ GLP1R P43220 4/20 0.63
▸ GCGR P47871 3/20 0.60
▸ NMBR P28336 1/20 0.60
▸ GRPR P30550 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Intermedine SCHEMBL20548027 1.00 MC4R (0.82) MC4RMC5RMC3RMC1RC5AR1
Intermedine SCHEMBL22076809 1.00 MC4R (0.82) MC4RMC5RMC3RMC1RC5AR1
SCHEMBL29534172 0.98 MC4R (0.78) MC4RMC5RMC3RMC1RC5AR1
SCHEMBL29430238 0.96 MC4R (0.78) MC4RMC5RMC3RMC1RC5AR1
SCHEMBL29533733 0.96 MC4R (0.78) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL29419548 0.96 MC4R (0.81) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL22463810 0.96 MC4R (0.81) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL29352792 0.96 MC4R (0.81) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL22463811 0.96 MC4R (0.81) MC4RMC5RMC3RMC1RC5AR1
Afamelanotide SCHEMBL29533175 0.95 MC4R (0.80) MC4RMC5RMC3RMC1RC5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117235175-A Ship product data cross-unit sharing method based on SCIM and IPDE 中国舰船研究设计中心 2023-12-15 — — CN claimed
CN-122020886-A Method, system, equipment and storage medium for designing residual stress of wheel disc 中国航发湖南动力机械研究所 2026-05-12 — — CN disclosed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20260062460-A1 METHODS FOR TREATING ACUTE CORONARY SYNDROME USING APOA-1 FUSION PROTEINS THERIPION, INC. (US) 2026-03-05 — — US disclosed
US-20260062709-A1 METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN LONZA AG (CH) 2026-03-05 — — US disclosed
US-12534511-B2 Serum albumin-binding fibronectin type III domains BRISTOL-MYERS SQUIBB COMPANY (US) 2026-01-27 — — US disclosed
US-12529088-B2 Helper factors for expressing proteins in yeast LONZA LTD (CH) 2026-01-20 — — US disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
US-20220049275-A1 SSI CELLS WITH PREDICTABLE AND STABLE TRANSGENE EXPRESSION AND METHODS OF FORMATION LONZA AG (CH) 2022-02-17 — — US disclosed
US-20220042064-A1 CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL LONZA LTD (CH) 2022-02-10 — — US disclosed
EP-3947695-A1 MUT- METHYLOTROPHIC YEAST Universität für Bodenkultur Wien (AT) 2022-02-09 — — EP disclosed
CN-114026239-A MUT-methanol nutritional yeast 维也纳自然资源与生命科学大学 2022-02-08 — — CN disclosed
CN-114026213-A Continuous blade type impeller 龙沙有限公司 2022-02-08 — — CN disclosed
US-11236520-B2 Customizable facility LONZA LTD (CH) 2022-02-01 — — US disclosed
EP-3942014-A1 CONTINUOUS BLADE IMPELLER Lonza Ltd. (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062460-A1 METHODS FOR TREATING ACUTE CORONARY SYNDROME USING APOA-1 FUSION PROTEINS PON1, APOB, APOL1 MC4R 4626/4885MC5R 4761/4885MC3R 4639/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS MC4R 616/4885MC5R 2160/4885MC3R 750/4885
US-12534511-B2 Serum albumin-binding fibronectin type III domains FN1, ALB, FGB MC4R 4106/4885MC5R 4148/4885MC3R 2261/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 MC4R 455/4885MC5R 1631/4885MC3R 1112/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 MC4R 1730/4885MC5R 1072/4885MC3R 1639/4885
US-20260062709-A1 METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN MRPL21, SET, RPS27A MC4R 4184/4885MC5R 4115/4885MC3R 4142/4885
US-12529088-B2 Helper factors for expressing proteins in yeast UPF1, ILF3, YIF1A MC4R 4874/4885MC5R 4877/4885MC3R 4876/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT MC4R 222/4885MC5R 409/4885MC3R 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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