Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | ADH5 | P11766 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22078001 | 0.83 | ESR1 (0.44) | ESR1MAOBTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL25492152 | 0.83 | ESR1 (0.44) | ESR1MAOBTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL22077997 | 0.83 | ESR1 (0.44) | ESR1MAOBTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL22078072 | 0.81 | ADH5 (0.53) | TBXAS1CYP3A4BAZ2BADH5KDM4E | |
| SCHEMBL22077254 | 0.80 | ESR1 (0.41) | ESR1MAOBTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL1238620 | 0.77 | ESR1 (0.67) | ESR1MAOBTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL1238616 | 0.77 | ESR1 (0.67) | ESR1MAOBTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL22078076 | 0.77 | TBXAS1 (0.53) | TBXAS1CYP3A4CYP2C19PLA2G4ABAZ2B | |
| Hydrochloric Acid SCHEMBL7328751 | 0.76 | ESR1 (0.65) | ESR1MAOBTBXAS1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7328757 | 0.76 | ESR1 (0.65) | ESR1MAOBTBXAS1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSNO THERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSNO THERAPEUTICS, INC. | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSR, CBR3, CBR1 | ESR1 1769/4885MAOB 181/4885TBXAS1 1031/4885 |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSR, CBR3, CBR1 | ESR1 1769/4885MAOB 181/4885TBXAS1 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.