Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL1500566 | 0.97 | NPC1 (0.50) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| Phenol SCHEMBL28243442 | 0.97 | NPC1 (0.50) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| Phenol SCHEMBL28169034 | 0.95 | NPC1 (0.49) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| Bicarbonate SCHEMBL29832424 | 0.88 | HPGD (0.46) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| Bicarbonate SCHEMBL28863262 | 0.86 | HPGD (0.45) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| Benzene SCHEMBL28168160 | 0.84 | NPC1 (0.52) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| Phenol SCHEMBL28328751 | 0.84 | SMN1; SMN2 (0.39) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| Biphenyl SCHEMBL28033347 | 0.83 | NPC1 (0.67) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| Acetic Acid SCHEMBL28619942 | 0.83 | HPGD (0.45) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| Acetic Acid SCHEMBL31758441 | 0.83 | HPGD (0.45) | HPGDSMN1; SMN2LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024142010-A1 | THERMOPLASTIC COMPOSITION AND ARTICLE WITH METALLIC VISUAL EFFECT | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2024-07-04 | — | — | WO | claimed |
| EP-3670603-B1 | 3D PRINTING HEAT RESISTANT SUPPORT MATERIAL | SHPP GLOBAL TECH BV (NL) | 2024-04-03 | — | — | EP | claimed |
| CN-111334895-B | 3D printing heat-resistant supporting material | 高新特殊工程塑料全球技术有限公司 | 2023-03-24 | — | — | CN | claimed |
| WO-2021021399-A1 | ADDITIVE MANUFACTURING ARTICLE AND METHOD | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-02-04 | — | — | WO | claimed |
| EP-3771723-A1 | ADDITIVE MANUFACTURING ARTICLE AND METHOD | SHPP Global Technologies B.V. (NL) | 2021-02-03 | — | — | EP | claimed |
| WO-2020160059-A1 | METHOD OF SEPARATING A COPOLYCARBONATE-BASED SUPPORT STRUCTURE FROM AN ADDITIVELY MANUFACTURED ARTICLE | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-08-06 | — | — | WO | claimed |
| EP-3689968-A1 | METHOD OF SEPARATING A COPOLYCARBONATE-BASED SUPPORT STRUCTURE FROM AN ADDITIVELY MANUFACTURED ARTICLE | SABIC Global Technologies B.V. (NL) | 2020-08-05 | — | — | EP | claimed |
| CN-111334895-A | 3D printing heat-resistant supporting material | 沙特基础工业全球技术有限公司 | 2020-06-26 | — | — | CN | claimed |
| EP-3670603-A1 | 3D PRINTING HEAT RESISTANT SUPPORT MATERIAL | SABIC Global Technologies B.V. (NL) | 2020-06-24 | — | — | EP | claimed |
| US-20200189180-A1 | 3D PRINTING HEAT RESISTANT SUPPORT MATERIAL | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2020-06-18 | — | — | US | claimed |
| WO-2024142010-A1 | THERMOPLASTIC COMPOSITION AND ARTICLE WITH METALLIC VISUAL EFFECT | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2024-07-04 | — | — | WO | disclosed |
| WO-2024142010-A1 | THERMOPLASTIC COMPOSITION AND ARTICLE WITH METALLIC VISUAL EFFECT | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2024-07-04 | — | — | WO | disclosed |
| US-11976195-B2 | Polycarbonate copolymer and associated film extrusion composition, extruded film, and capacitor | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2024-05-07 | — | — | US | disclosed |
| CN-117999309-A | Film extrusion composition and related extruded film, metallized film and capacitor | 高新特殊工程塑料全球技术有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20240117185-A1 | POLYCARBONATE COPOLYMER AND ASSOCIATED FILM EXTRUSION COMPOSITION, EXTRUDED FILM, AND CAPACITOR | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2024-04-11 | — | — | US | disclosed |
| EP-3670603-A1 | 3D PRINTING HEAT RESISTANT SUPPORT MATERIAL | SABIC Global Technologies B.V. (NL) | 2020-06-24 | — | — | EP | disclosed |
| US-20200189180-A1 | 3D PRINTING HEAT RESISTANT SUPPORT MATERIAL | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2020-06-18 | — | — | US | disclosed |
| US-20200189180-A1 | 3D PRINTING HEAT RESISTANT SUPPORT MATERIAL | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2020-06-18 | — | — | US | disclosed |
| CN-107429054-A | Fire-retardant combination, its manufacture method and include its product | 沙特基础工业全球技术有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-105612035-A | Device for making additives packages ('masterbatch') for thermoplastic compositions | SABIC GLOBAL TECHNOLOGIES BV | 2016-05-25 | — | — | CN | disclosed |