Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL1500566 | 1.00 | NPC1 (0.50) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| Phenol SCHEMBL28169034 | 0.98 | NPC1 (0.49) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| Phenol SCHEMBL22077487 | 0.97 | HPGD (0.50) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| Benzene SCHEMBL28168160 | 0.87 | NPC1 (0.52) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| Biphenyl SCHEMBL28033347 | 0.86 | NPC1 (0.67) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| Naphthalene SCHEMBL28230715 | 0.84 | NPC1 (0.50) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL8571092 | 0.84 | NPC1 (0.50) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| Bicarbonate SCHEMBL15652769 | 0.83 | HPGD (0.46) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| Methyl Alcohol SCHEMBL9328801 | 0.83 | ALDH1A1 (0.48) | NPC1RAB9AHPGDLMNAKMT2A | |
| SCHEMBL7102666 | 0.83 | ALDH1A1 (0.52) | NPC1RAB9AHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463484-A | Thermoplastic polyimide, the method for manufacturing it and product prepared therefrom | 沙特基础工业全球技术有限公司 | 2018-08-28 | — | — | CN | disclosed |