Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 9/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22077639 | 0.86 | CTSK (0.46) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL16281191 | 0.86 | CTSK (0.46) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL9911449 | 0.85 | CA1 (0.52) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL10464366 | 0.82 | CTSK (0.46) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL26104612 | 0.82 | CTSK (0.46) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL20757550 | 0.82 | CTSK (0.49) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL1809284 | 0.80 | CTSK (0.47) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL102361 | 0.80 | CTSK (0.47) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL1809285 | 0.80 | CTSK (0.47) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL2293242 | 0.79 | CTSK (0.46) | SYKCTSKCTSSCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020115506-A1 | QUINOLINONE AND BENZOXAZINE DERIVATIVES AS MUSCARINIC M1 AND/OR M4 RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-06-11 | — | — | WO | disclosed |