Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911449 | 0.88 | CA1 (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL20757550 | 0.85 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL30980418 | 0.84 | CA1 (0.45) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8561571 | 0.84 | CA1 (0.53) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8560322 | 0.84 | CA1 (0.53) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL102361 | 0.83 | CTSK (0.47) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL1809284 | 0.83 | CTSK (0.47) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL1809285 | 0.83 | CTSK (0.47) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL22077873 | 0.82 | SYK (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL20886481 | 0.82 | CA1 (0.44) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943567-A | EFFECTIVE AGAINST PSEUDOMONAS | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| EP-0293771-A2 | Cephalosporin compound and pharmaceutical composition thereof | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1988-12-07 | — | — | EP | disclosed |