Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | HAT1 | O14929 | 5/20 | 0.41 |
| ▸ | EP300 | Q09472 | 5/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ADH5 | P11766 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25492057 | 0.81 | PRMT5 (0.40) | TBXAS1PRMT5WDR77HAT1EP300 | |
| SCHEMBL20536555 | 0.81 | ADH5 (0.54) | TBXAS1ADH5 | |
| SCHEMBL30772949 | 0.81 | ADH5 (0.54) | TBXAS1ADH5 | |
| SCHEMBL22078076 | 0.77 | TBXAS1 (0.53) | TBXAS1PRMT5WDR77NPY5RKDM4E | |
| SCHEMBL23839233 | 0.75 | CYP19A1 (0.53) | TBXAS1PRMT5WDR77MEN1MAPT | |
| SCHEMBL31104422 | 0.75 | TBXAS1 (0.52) | TBXAS1NPY5RKDM4EALDH1A1MAPT | |
| SCHEMBL23391734 | 0.75 | TBXAS1 (0.52) | TBXAS1NPY5RKDM4EALDH1A1MAPT | |
| SCHEMBL22078068 | 0.75 | TBXAS1 (0.50) | TBXAS1PRMT5WDR77HAT1EP300 | |
| SCHEMBL20535874 | 0.75 | HTT (0.62) | MEN1ALDH1A1MAPTKMT2AADH5 | |
| SCHEMBL30772966 | 0.75 | HTT (0.62) | MEN1ALDH1A1MAPTKMT2AADH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSNO THERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSNO THERAPEUTICS, INC. | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSR, CBR3, CBR1 | TBXAS1 1031/4885PRMT5 506/4885WDR77 3715/4885 |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSR, CBR3, CBR1 | TBXAS1 1031/4885PRMT5 506/4885WDR77 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.