SCHEMBL22078673

SCHEMBL22078673

CCCCCCCCc1ccc(/C=N/c2ccccc2Br)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
HTR2A P28223 2/20 0.41
LMNA P02545 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1879318 0.80 CYP3A4 (0.41) CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B
SCHEMBL8624249 0.80 LMNA (0.57) CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B
SCHEMBL1871731 0.80 CYP3A4 (0.54) CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B
SCHEMBL7769756 0.80 CYP3A4 (0.54) CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B
SCHEMBL11812381 0.78 CYP3A4 (0.51) CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B
SCHEMBL11153670 0.78 CYP3A4 (0.51) CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B
SCHEMBL12416633 0.77 CYP3A4 (0.62) CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B
SCHEMBL10764013 0.77 CYP3A4 (0.62) CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B
SCHEMBL3623036 0.77 CYP3A4 (0.62) CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B
SCHEMBL1877158 0.77 CYP3A4 (0.57) CYP3A4CYP2D6CYP2C9ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020116904-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-06-11 WO disclosed